Both sides will want to put FA Cup exits behind them – Reading had won nine of their last 11 league games before losing to Manchester United at the weekend.
QPR were beaten at home by Blackburn in the Cup but are looking for their third league win in a row after victories against Wolves and Ipswich.
However, Ian Holloway is in the middle of a rebuild of his squad and, despite a few injuries, the Royals would be expected to prevail.
Reading – Captain Paul McShane, who missed the FA Cup defeat at Manchester United, is again ruled out with a wrist injury, though he is back in training. Naija and Bet
Winger Callum Harriott is expected to miss the next four to six weeks with a hamstring injury, while goalkeeper Anssi Jaakkola and midfielder Stephen Quinn and striker Deniss Rakels are all sidelined.
The Royals are close to signing defender Tiago Ilori from Liverpool.
Queens Park Rangers – QPR could give a debut to winger Kazenga LuaLua, who signed on loan from Brighton this week.
Playmaker Tjaronn Chery remains out of favour while he seeks a move away but full-back Darnell Furlong and midfielder Michael Doughty could be in the squad after being recalled from loan spells at Swindon.
Defenders Steven Caulker and Jack Robinson remain absent.
Reading have won 9 of their last 11 matches in Championship.
Reading have seen under 2.5 goals in their last 6 home matches against QPR in all competitions.
There have been over 2.5 goals scored in 8 of Reading’s last 9 Championship games.
Reading have scored at least 3 goals in their last 3 matches
There have been over 2.5 goals scored in QPR’s last 3 Championship games.