Lyon are in a rough patch at the moment but will be boosted by the return of star player Alexandre Lacazette.
They need the France international to fire as soon as possible after losing three of their last four matches in all competitions.
They have got on the scoresheet in all 15 home matches since moving into their new stadium and won 12 of those fixtures.
Juventus, meanwhile, have won their last five matches coming into this fixture although they were made to work hard at the weekend to maintain their five point lead over Roma. Naija and Bet
The Serie A champions have won three of their last four against French sides and should be confident of overcoming a Lyon side short on confidence and form.
Lyon – Nabil Fekir was sent off against Nice on Friday but his suspension will not carry over in European competition.
Alexandre Lacazette made his return to first-team action in the 2-0 defeat after a month out injured and he will be in contention to start against Juventus.