Manchester United earned a 1-1 draw in terrible conditions in the reverse leg back in Russia and are favorites to progress here.
Rostov are unbeaten in their last seven competitive matches, although picking up results away from home has proven extremely hard.
The Russian outfit have only won two competitive matches on the road all season and elimination from the Europa League is expected on Thursday night.
Manchester United – Jose Mourinho will recall on the services of Zlatan Ibrahimovic on Thursday after the Manchester United No.9 missed Monday’s defeat to Chelsea in the FA Cup through suspension.
Anthony Martial and Wayne Rooney are both ruled out again after failing to overcome injuries that saw the duo miss Monday’s trip to Stamford Bridge. Naija and Bet
Roma have lost three of their last four matches in all competitions and their surprise 2-1 defeat at home to Napoli at the weekend would have knocked confidence.
Lyon, on the contrary, have been scoring goals for fun of late. They have scored 25 goals in their last five matches in all competitions, although they were held 1-1 by Bordeaux at the weekend.
Roma have won five of their nine matches against French sides in the past and have only lost one.
This is an evenly poised fixture which could be hinge on the performances of Alexandre Lacazette for Lyon or Edin Dzeko for Roma.
Lyon – Maciej Rybus was left out of the squad that drew with Bordeaux at the weekend, but it remains to be seen whether this decision was taken to have the defender ready for Thursday. Predict today’s Matches on NaijaBet.com
Bruno Génésio has no concerns ahead of Thursday’s welcome of Roma.
Rostov have lost only once in their last seven European home games and even beat Bayern Munich in the Champions League group stages at the start of the season.
The Russian side warmed up for this fixture with a 6-0 win against Tom Tomsk.
Manchester United have kept four successive clean sheets in the Europa League, only Napoli have ever managed five in a row.
United have drawn six of their nine meetings with Russian sides in the past and a tough game is expected here. Naija and Bet
FC Rostov – First choice goalkeeper Soslan Dzhanaev has not featured since December and could miss out on Thursday.
No unexpected changes are expected from the Russian side.
Manchester United have not lost in 12 European home matches against sides from France, while Saint-Etienne have lost each of their last three matches in England.
The French side not be underestimated, however. Saint-Etienne are unbeaten in all 10 of their Europa League games this season and have four of their five away matches in the competition.
Saint-Etienne are currently fifth in Ligue 1 where only Paris Saint-Ger- main (19) have conceded fewer goals (18). United are been guilty of missing plenty of chances this season and they will need to improve their form in front of goal here in order to try and get the job done in the first leg. Place Bet on NaijaBet.com
Manchester United – Jose Mourinho is expected to name a near full strength side for the first leg of their Europa League clash against Saint-Etienne, with a view to making changes in the FA Cup at the weekend.
Marcos Rojo and Phil Jones missed out at the weekend and are still injury doubts for Thursday’s clash.
Villarreal have only lost two of their last 14 matches in all competitions but have struggled to turn draws into wins. In fact, half of those matches have ended in a draw.
The Yellow Submarines have only won one of their last five in the Europa League and they must change that run to have any chance of overcoming Roma in this tie.
Roma have won nine of their last 11 matches and have kept a clean sheet in five of their last seven away matches in all competitions. Luciano Spalletti’s side will be happy to come away with a draw here and will fancy their chances of winning in the return leg at home. Naija and Bet
Villarreal – Roberto Soriano was sent off at the weekend but his suspension in La Liga will not prohibit his involvement in Thursday’s meeting with Roma.
Tottenham are winless in four matches in Belgium and have only won one of their last seven away matches in the Europa League. Mauricio Pochettino’s side also come into this match off the back of a dreadful 2-0 defeat to Liverpool.
Gent’s results have been disappointing this season but their home form has been strong. They did lose last time out on home soil but that was only their third defeat in 19 home matches in all competitions this season.
Tottenham are favourites to come through this tie but may still have some work to do when they return to London for the second leg.
Gent – No surprises are expected from Gent, who are expected to line up with much of the same team that has got them this far in the competition. Renato Neto is one booking away from suspension. NaijaBet.com
The outcome of this fixture could well decide who finishes top of Group K. Sparta Prague go into this fixture two points clear of Southampton, having won each of their last three games in the competition.
They come into this match having won each of their last five home matches, where they have also kept a clean sheet in the last four of those.
Southampton eased to a 3-0 win over Thursday’s opponents in the reverse fixture at the start of the campaign, but have suffered a wobble of late. They have only won three of their last 10 matches in all competitions and have only won one of eight away matches this season. Naijabet.com
They haven’t even scored a goal on the road in their first two away matches in the Europa League and will need an improved performance on Thursday to have a shot at returning to England with all three points.
Southampton’s good run of form looks to be coming to an end after only managing to win two of their last seven matches in all competitions.
They were particularly disappointing against Chelsea at the weekend and things do not get easier when they welcome Inter, despite the fact the Serie A giants are in turmoil.
Inter managed a 1-0 win on home soil against Southampton last month but have only won two of their last eight matches in all competitions. They have also lost on their last two visits to England.
Southampton are unbeaten in six European home games, a run that goes back to 1981. Nevertheless, it will take a huge performance for them to win here, but it will be an occasion to savour for their fans. Naijabet.com
Southampton – are expected to be without Cedric Soares, Jeremy Pied, Florin Gardos and Matt Targett for Thursday’s reception of Inter. Gardos stepped up his return to first team action with 90 minutes for the U23s.
Claude Puel has eased Sofiane Boufal into the team following his injury but may feel it is the right time to have his club-record signing another start here.
Inter Milan Managerless Inter can welcome Andrea Ranocchia back from suspension after he missed their 1-0 win over Southampton through suspension, but they will now be without Marcelo Brozovic who was sent off in that win.
Geoffrey Kondogbia, Joao Mario, Stevan Jovetic and Gabriel are not included in Inter’s Europa League squad and will not feature here.
Gary Medel missed their 1-0 defeat to Sampdoria at the weekend through suspension but is available to feature on Thursday, but Felipe Melo is out because of injury.
All in all, Inter may not make many changes to the side that beat Southampton last time out, but caretaker manager Stefano Vecchi could tinker with some elements of the team.
There have been under 2.5 goals scored in 5 of Southampton‘s last 6 games in UEFA Europa League.
As at this post Southampton has 1.77 odd to win the match on NaijaBet while Inter Milan has 4.56 odd to win the match also, while the odd to draw the match is 3.54.
Inter’s Europa League campaign has been a disaster. They’ve lost both of their opening two matches and will welcome a confident Southampton side having lost each of their last three matches.
Southampton are unbeaten in their last seven matches and have won five of those, only conceding one goal in that time. The Saints are one of just three sides yet to concede in the Europa League group stages.
The Saints could inflict further misery on Inter, although that would mean becoming the first Premier League side in four matches to triumph against Inter in Milan. Naijabet.com
Inter Milan – Geoffrey Kondogbia, Joao Mario, Stevan Jovetic and Gabriel are not included in Inter’s Europa League squad and will not feature here.